(S,R,S)-AHPC-C4-NH2 hydrochloride ( VH032-C4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 28 )

产品货号. M27010 CAS No. 2245697-83-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

(S,R,S)-AHPC-C4-NH2 hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
产品描述

(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
同义词

VH032-C4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 28
通路

Others
靶点

Other Targets
受体

LIN28
研究领域

——
适应症

——

CAS Number

2245697-83-8
分子量

566.2
分子式

C27H40ClN5O4S
纯度

>98% (HPLC)
溶解度

——
SMILES

O=C(N[C@@H](C(C)(C)C)C(N1C[C@H](O)C[C@H]1C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)=O)CCCCN.[H]Cl
化学全称

——

1.VG D’Agostino, et al. Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery. Slas Discovery, 2019.

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